Manchester City will take on Real Madrid, while Barcelona are drawn against Napoli.
Paris Saint-Germain who beat Real Madrid to first place in Group A will take on Borussia Dortmund, while Cristiano Ronaldo’s Juventus will battle Lyon.
Five-time winners Bayern Munich will meet Chelsea in a rematch of the 2011-12 Champions League final, when the Blues won 4-3 on penalties following a 1-1 draw after extra time.
The first round of matches are scheduled to take place on February 18-19 and February 25-26. The second-leg fixtures begin on March 10-11, and the final round-of-16 games will take place on March 17-18.
Borussia Dortmund vs. Paris Saint-Germain
Real Madrid vs. Manchester City
Atalanta vs. Valencia
Atletico Madrid vs. Liverpool
Chelsea vs. Bayern Munich
Lyon vs. Juventus
Tottenham Hotspur vs. RB Leipzig
Napoli vs. Barcelona